Evorel is a hormonal estrogenic medicine, which indistinguishable to the endogenous estradiol created by the ovaries (framed in the assortment of ladies, beginning with the main monthly cycle and closure with the menopause time frame). Manufactured estradiol is a white crystalline powder. It is for all intents and purposes insoluble in water, effectively dissolvable in alcohol, a solvent in acetone, dioxane and other natural solvents. It is hard to dissolve this medicine in vegetable oils.
In medical practice, it is used in the form of estradiol hemihydrate and esters (benzoate, propionate).
Evorel is used in different dosage forms: transdermal gel, injections, oil, nasal spray, coated tablets, and other.
Do not use Evorel if you have Bronchial asthma, diabetes mellitus, migraine, epilepsy, arterial hypertension, and heart failure, acute or chronic liver disease.
Side effects of Evorel
From the nervous system and sensory organs: dizziness, headache, migraine, depression, chorea, blurred vision (change in the curvature of the cornea), and discomfort when wearing contact lenses.
For the cardiovascular system and blood (hematopoiesis, hemostasis): increased blood pressure, thromboembolism.
On the part of the gastrointestinal tract: nausea, vomiting (mainly of central genesis when using high doses), pain in the epigastric region, flatulence, diarrhea, anorexia, cholestatic jaundice, cholelithiasis, hepatitis, pancreatitis, intestinal and biliary colic.
Before using Evorel, you need a complete general medical and gynecological examination, including the study of the abdominal cavity and small pelvis, mammary glands, measurement of blood pressure, and endometrial cytology. It is necessary to exclude pregnancy. With long-term therapy, such an examination should be carried out every 6-12 months.